Question 1

As in glycolysis and the degradation of glucose, the degradation of fatty acids also requires an initial investment of ATP energy. State the reaction or reactions where ATP energy is needed before fatty acids can be oxidized.

Accepted Answer

The enzyme fatty acyl-CoA synt...

Question 2

In the fatty acid synthesis pathway, how many ATPs and NADPHs are needed to add two carbons to the growing fatty acid chain starting with an acetyl-CoA?

Accepted Answer

One ATP to activate ...

Question 3

The rate-limiting reaction is catalyzed by in the synthesis of saturated fatty acids in the .

Accepted Answer

A)   fatty acid synthase; cytosol
B)   fatty acid synthase; mitochondrion
C)   acetyl-CoA carboxylase; cytosol
D)   citrate synthase; mitochondrionE) B) and C)
F) B) and D)

Question 4

How many high-energy FADH2 and NADH molecules, respectively, are made from each pass through the  β\betaβ -oxidation pathway?

Accepted Answer

A)   1 FADH2; 2 NADH
B)   1 FADH2; 0 NADH
C)   0 FADH2; 2 NADH
D)   1 FADH2; 1 NADH E) A) and D)
F) None of the above

Question 5

The NADPH required by the fatty acid synthesis pathway comes from the

Accepted Answer

A)   pentose phosphate pathway and the shuttle of citrate from the mitochondria.
B)   mitochondria.
C)   breakdown of glucose.
D)   TCA cycle and the shuttle of citrate from the mitochondria.E) A) and B)
F) B) and D)

Question 6

The synthesis of both triacylglycerols and membrane phospholipids occurs from which immediate precursor?

Accepted Answer

A)   phosphatidic acid
B)   glycerol
C)   phosphatidylserine
D)   diacylglycerolE) All of the above
F) B) and C)

Question 7

The introduction of 1 4CO2 into a cell actively synthesizing fatty acids results in 1 4C labeled

Accepted Answer

A)   malonyl-CoA.
B)   acetyl-CoA.
C)   acyl-CoA.
D)   palmitate.E) All of the above
F) B) and C)

Question 8

Draw the overall balanced reaction for the synthesis of palmitic acid (16:0) from acetyl-CoA precursors. Please include all the high-energy cofactors required for the process.

Accepted Answer

8 acetyl-CoA + 7 ATP + 14 NADP...

Question 9

What molecule is the odd chain fatty acid product propionyl-CoA converted into?

Accepted Answer

A)   butyryl-CoA
B)   succinyl-CoA
C)   citrate
D)   palmitateE) A) and B)
F) C) and D)

Question 10

Which enzyme is responsible for assembly of palmitate from activated acetyl-CoA fragments?

Accepted Answer

A)   acyl-CoA dehydrogenase
B)   acetyl-CoA carboxylase
C)   fatty acyl-CoA synthetase
D)   fatty acid synthaseE) A) and D)
F) A) and C)

Question 11

How many total NADH + FADH2s are made in the  β\betaβ -oxidation pathway from the breakdown of the following fatty acid to all acetyl-CoAs? 2s are made in the  \beta -oxidation pathway from the breakdown of the following fatty acid to all acetyl-CoAs?   A)  6 B)  8 C)  4 D)  2 " class="answers-bank-image d-inline" rel="preload" >

Accepted Answer

A)   6
B)   8
C)   4
D)   2 E) A) and B)
F) A) and C)

Question 12

The regulation of Acetyl-CoA carboxylase is

Accepted Answer

A)   activated by glucagon.
B)   activated by acyl-CoA binding.
C)   stimulated by citrate.
D)   inactivated by insulin.E) A) and D)
F) None of the above

Question 13

Name the enzyme in the following reaction:

Accepted Answer

Phosphatid...

Question 14

Both the synthesis and  β\betaβ -oxidation of saturated fatty acids

Accepted Answer

A)   require FAD.
B)   require NADPH.
C)   occur in the cytosol.
D)   involve acetyl-CoA. E) A) and D)
F) B) and C)

Question 15

Which is found in the ketone body pathway?

Accepted Answer

A)   succinyl-CoA.
B)   propionyl-CoA.
C)   dihydroxyacetone phosphate.
D)   hydroxybutyrate.E) C) and D)
F) None of the above

Question 16

What enzyme catalyzes the following fatty acid synthesis reaction?

Accepted Answer

A)   fatty acid synthase
B)   fatty acyl-CoA synthetase
C)   fatty acyl-CoA dehydrogenase
D)   acetyl-CoA carboxylaseE) A) and B)
F) B) and C)

Question 17

The sterol regulatory element (SRE)  is a(n)  and the sterol regulatory element binding protein (SREBP)  is a(n)  _.

Accepted Answer

A)   allosteric activator; enzyme
B)   transport activator; transport protein
C)   receptor; hormone
D)   DNA promoter; transcription activatorE) A) and B)
F) All of the above

Question 18

The synthesis of fatty acids requires which cofactor?

Accepted Answer

A)   FADH2
B)   NADH
C)   thiamine pyrophosphate (TPP) 
D)   NADPHE) C) and D)
F) A) and D)

Question 19

About more ATPs can be obtained from one 16:0 fatty acid than from one glucose molecule.

Accepted Answer

A)   32
B)   106
C)   2
D)   75E) B) and D)
F) A) and D)

Question 20

What extra enzyme types are often required in the degradation of polyunsaturated fats by the  β\betaβ -oxidation pathway?

Accepted Answer

A)   reductase and isomerase
B)   hydrolase and isomerase
C)   oxidoreductase and reductase
D)   synthase and isomerase E) A) and D)
F) B) and C)

Exam 16: Lipid Metabolism

The synthesis of fatty acids requires which cofactor?

Correct Answer
verified

Correct Answer
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Which is found in the ketone body pathway?

Correct Answer
verified

The rate-limiting reaction is catalyzed by in the synthesis of saturated fatty acids in the .

Correct Answer
verified

What extra enzyme types are often required in the degradation of polyunsaturated fats by the $\beta$ -oxidation pathway?

Correct Answer
verified

What enzyme catalyzes the following fatty acid synthesis reaction?

Correct Answer
verified

The regulation of Acetyl-CoA carboxylase is

Correct Answer
verified

Both the synthesis and $\beta$ -oxidation of saturated fatty acids

Correct Answer
verified

Which enzyme is responsible for assembly of palmitate from activated acetyl-CoA fragments?

Correct Answer
verified

In the fatty acid synthesis pathway, how many ATPs and NADPHs are needed to add two carbons to the growing fatty acid chain starting with an acetyl-CoA?

Correct Answer
verified
One ATP to activate ...
View Answer

As in glycolysis and the degradation of glucose, the degradation of fatty acids also requires an initial investment of ATP energy. State the reaction or reactions where ATP energy is needed before fatty acids can be oxidized.

Correct Answer
verified
The enzyme fatty acyl-CoA synt...
View Answer

The introduction of ^{1 4}CO₂ into a cell actively synthesizing fatty acids results in ^{1 4}C labeled

Correct Answer
verified

Draw the overall balanced reaction for the synthesis of palmitic acid (16:0) from acetyl-CoA precursors. Please include all the high-energy cofactors required for the process.

Correct Answer
verified
8 acetyl-CoA + 7 ATP + 14 NADP...
View Answer

The sterol regulatory element (SRE) is a(n) and the sterol regulatory element binding protein (SREBP) is a(n) _.

Correct Answer
verified

The NADPH required by the fatty acid synthesis pathway comes from the

Correct Answer
verified

What molecule is the odd chain fatty acid product propionyl-CoA converted into?

Correct Answer
verified

Name the enzyme in the following reaction:

Correct Answer
verified
Phosphatid...
View Answer

How many high-energy FADH₂ and NADH molecules, respectively, are made from each pass through the $\beta$ -oxidation pathway?

Correct Answer
verified

About more ATPs can be obtained from one 16:0 fatty acid than from one glucose molecule.

Correct Answer
verified

The synthesis of both triacylglycerols and membrane phospholipids occurs from which immediate precursor?

Correct Answer
verified

Exam 16: Lipid Metabolism

The synthesis of fatty acids requires which cofactor?

Correct AnswerverifiedShow Answer

How many total NADH + FADH2s are made in the β\betaβ -oxidation pathway from the breakdown of the following fatty acid to all acetyl-CoAs?

Correct AnswerverifiedShow Answer

Which is found in the ketone body pathway?

Correct AnswerverifiedShow Answer

The rate-limiting reaction is catalyzed by in the synthesis of saturated fatty acids in the .

Correct AnswerverifiedShow Answer

What extra enzyme types are often required in the degradation of polyunsaturated fats by the β\betaβ -oxidation pathway?

Correct AnswerverifiedShow Answer

What enzyme catalyzes the following fatty acid synthesis reaction?

Correct AnswerverifiedShow Answer

The regulation of Acetyl-CoA carboxylase is

Correct AnswerverifiedShow Answer

Both the synthesis and β\betaβ -oxidation of saturated fatty acids

Correct AnswerverifiedShow Answer

Which enzyme is responsible for assembly of palmitate from activated acetyl-CoA fragments?

Correct AnswerverifiedShow Answer

In the fatty acid synthesis pathway, how many ATPs and NADPHs are needed to add two carbons to the growing fatty acid chain starting with an acetyl-CoA?

Correct AnswerverifiedOne ATP to activate ...View AnswerShow Answer

As in glycolysis and the degradation of glucose, the degradation of fatty acids also requires an initial investment of ATP energy. State the reaction or reactions where ATP energy is needed before fatty acids can be oxidized.

Correct AnswerverifiedThe enzyme fatty acyl-CoA synt...View AnswerShow Answer

The introduction of 1 4CO2 into a cell actively synthesizing fatty acids results in 1 4C labeled

Correct AnswerverifiedShow Answer

Draw the overall balanced reaction for the synthesis of palmitic acid (16:0) from acetyl-CoA precursors. Please include all the high-energy cofactors required for the process.

Correct Answerverified8 acetyl-CoA + 7 ATP + 14 NADP...View AnswerShow Answer

The sterol regulatory element (SRE) is a(n) and the sterol regulatory element binding protein (SREBP) is a(n) _.

Correct AnswerverifiedShow Answer

The NADPH required by the fatty acid synthesis pathway comes from the

Correct AnswerverifiedShow Answer

What molecule is the odd chain fatty acid product propionyl-CoA converted into?

Correct AnswerverifiedShow Answer

Name the enzyme in the following reaction:

Correct AnswerverifiedPhosphatid...View AnswerShow Answer

How many high-energy FADH2 and NADH molecules, respectively, are made from each pass through the β\betaβ -oxidation pathway?

Correct AnswerverifiedShow Answer

About more ATPs can be obtained from one 16:0 fatty acid than from one glucose molecule.

Correct AnswerverifiedShow Answer

The synthesis of both triacylglycerols and membrane phospholipids occurs from which immediate precursor?

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

What extra enzyme types are often required in the degradation of polyunsaturated fats by the $\beta$ -oxidation pathway?

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Both the synthesis and $\beta$ -oxidation of saturated fatty acids

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
One ATP to activate ...
View Answer

Correct Answer
verified
The enzyme fatty acyl-CoA synt...
View Answer

The introduction of ^{1 4}CO₂ into a cell actively synthesizing fatty acids results in ^{1 4}C labeled

Correct Answer
verified

Correct Answer
verified
8 acetyl-CoA + 7 ATP + 14 NADP...
View Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
Phosphatid...
View Answer

How many high-energy FADH₂ and NADH molecules, respectively, are made from each pass through the $\beta$ -oxidation pathway?

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified