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Reactivation of latent in immunosuppressed individuals may result in disease of the brain known as progressive multifocal leukoencephalopathy (PLM) .


A) HHV- 6
B) B19 virus
C) JC virus
D) HHV- 8
E) BK virus

F) A) and E)
G) B) and C)

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Skin lesions described as "dewdrops on rose petals" are characteristic of (chickenpox/shingles).

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Which of the following statements is true of both molluscum contagiosum and smallpox?


A) The causative agent is a large dsDNA virus with a complex capsid.
B) A genital form of the disease exists.
C) The rash forms fluid- filled vesicles that become pustules.
D) It has a morality rate of 20%.
E) A vaccine is available.

F) None of the above
G) A) and C)

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A patient is brought into the ER in a coma. Upon inspection, the physician sees evidence of many new tattoos, as well as yellowing of the skin and eyes. What is the most likely cause of the patient's condition?

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The patient is suffering from viral hepa...

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The large size of poxviruses allows them to


A) travel in droplets.
B) be easily isolated in infected cells.
C) attach to both animal and human cells.
D) be potential vectors for introduction of genetic material in vaccinations for gene therapy.
E) provoke a strong immune response in the host.

F) A) and B)
G) A) and C)

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Adenoviruses are so named because they infect only adenoid cells in humans.

A) True
B) False

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Erythema infectiosum is a dangerous but treatable disease.

A) True
B) False

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Hepatitis B virus replicates in liver cells and is released by (exocytosis/lysis), which contributes to the infection becoming chronic.

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A scientist discovers a new virus that causes mild respiratory disease in humans. He is able to isolate, purify, and characterize the virus. The virus preparation contains double- stranded DNA and no lipid. To which of the following virus families does this new virus likely belong?


A) Herpesviridae
B) Papillomarviridae
C) Adenoviridae or Papillomaviridae
D) Adenoviridae
E) Herpesviridae or Poxviridae

F) None of the above
G) C) and D)

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Individuals who have had chickenpox may develop (cancer/shingles/whitlows) later in life if they experience severe stress or immune suppression.

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For protection from infection with genital herpes, condoms need to be used only when there is an active lesion.

A) True
B) False

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Which of the following characteristics are common to Poxviridae, Herpesviridae, and Hepadnaviridae?


A) double- stranded DNA in the virion
B) the presence of an envelope
C) a complex capsid
D) double- stranded DNA in the virion with a complex capsid
E) double- stranded DNA in the virion and the presence of an envelope

F) B) and C)
G) C) and D)

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Which among the following are the largest DNA viruses that infect humans?


A) Herpesviridae
B) Poxviridae
C) Adenoviridae
D) Papillomaviridae
E) Polyomaviridae

F) A) and D)
G) A) and E)

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Nearly everyone appears to be infected with polyomaviruses BK and JC by the age of 15.

A) True
B) False

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In infections with human herpesvirus (1/2/3/4), the virus becomes latent in B lymphocytes and suppresses apoptosis, thus providing one source of lymphomas associated with this virus.

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Human herpesvirus 4 (EBV) has been implicated as an etiological agent in some cases of Hodgkin's lymphoma.

A) True
B) False

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A young man goes to a clinic complaining of discomfort in his foot, especially when standing. Upon examination, the clinician observes raised bumps with rough surfaces on the sole of his foot. These lesions are consistent with


A) shingles.
B) molluscum contagiosum.
C) erythema infectiosum.
D) warts.
E) whitlow.

F) A) and D)
G) A) and C)

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Which of the following increases the risk of permanent liver damage with hepatitis B infection?


A) coinfection with HHV- 6
B) coinfection with human herpesvirus 4
C) coinfection with hepatitis D virus
D) coinfection with human herpesvirus 4 and hepatitis D virus
E) coinfection with hepatitis D virus and HHV- 6

F) A) and E)
G) A) and B)

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Infection of the respiratory system by may develop into symptoms of a common cold.


A) cytomegaloviruses
B) adenoviruses
C) polyomaviruses
D) papillomaviruses
E) parvoviruses

F) A) and C)
G) A) and E)

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As the name implies, polyomaviruses are common causes of viral cancers in humans.

A) True
B) False

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